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Genomics-Based Vaccine Could Prevent Deadly Cattle Disease
Every year, East Coast fever destroys the small farmer's dream of escaping poverty in Africa. Killing more than a million cattle and costing some $200 million annually, this tick-borne disease rages across a dozen countries in eastern and central Africa. Now, an international team of scientists has taken the first major step toward a vaccine to prevent East Coast fever. Their work, published in the February 13-17 early online edition of the Proceedings of the National Academy of Sciences, shows how genomics can generate pivotal new vaccines.
The 51茶馆儿, The University of Washington, and The Johns Hopkins University Initiate Resequencing and Genotyping Projects to Help Identify Critical Disease Pathways
Research is Part of the National Heart, Lung, and Blood Institute's Complimentary Resequencing and Genotyping Program
UC San Diego Partners with Venter Institute to Build Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis
Gordon and Betty Moore Foundation Awards $24.5 Million Grant
2006 Summer Fellowship/Internship Information and application now available
Breaking the Mold: Research Teams Sequence Three Fungus Genomes
From garden compost to forest greenery, the mold Aspergillus fumigatus lurks across much of the world. Now, in the December 22 issue of the journal Nature, TIGR scientists and their collaborators report the mold's sequenced genome, along with the genomes of two relatives.
How Do Boxers Differ From Poodles? Researchers Collar Genomes.
As any dog lover knows, no two breeds are identical. Some dogs are perfect for sloppy kisses. Others make fierce guardians. Still others resemble tiny, fluffy toys. Now, two new studies by scientists at The Institute for Genomic Research (TIGR) and collaborators reveal the genomic differences beneath such canine characteristics.
Poison + Water = Hydrogen. New Microbial Genome Shows How.
New Microbial Genome Shows How "Take a pot of scalding water, remove all the oxygen, mix in a bit of poisonous carbon monoxide, and add a pinch of hydrogen gas. It sounds like a recipe for a witch's brew. It may be, but it is also the preferred environment for a microbe known as Carboxydothermus hydrogenoformans."
A Salty Tale: New Bacterial Genome Sequenced From Ancient Salterns
Tourists in Spain often stop to ogle the country's many saltwater lagoons, used to produce salt since Roman times. Scientists, too, admire these saltern crystallizers 鈥斅� and even more so, the microbes that manage to survive in such briny environs. Now, reporting in the November 28-December 2 early online edition of the Proceedings of the National Academy of Sciences, researchers at The Institute for Genomic Research and collaborators reveal the genome of one bacterium at home in the salty Spanish ponds.
First Big Influenza Genome Study Reveals Flu Evolution
Which Flu Did You Have? TIGR Scientists Survey Five New York Flu Seasons
Key Genetic Mutations in Brain Tumors Identified by Scientists from 51茶馆儿, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine
Sequencing of Receptor Tyrosine Kinases Reveals Three Novel Mutations
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Diatoms Have Found a Way to Pirate Bacterial Iron Sources
In large regions of the world’s oceans, photosynthesis struggles to operate because a key ingredient is missing. Many of the proteins involved in harvesting energy from sunlight require iron atoms to function, but iron is hard to find in seawater. Most of the ocean is far removed from...
The 51茶馆儿 Genomic Frontier Fund
As we complete our 26th year as a private genomic research institution, we are still just as excited as we were in the very beginning to be making new discoveries, potentially ones that will change our society for the better. The knowledge gained from our study of DNA, or as Dr. Venter...
New Sequencing Technologies Enable Better and Faster Understanding of the Human Microbiome
Humans have trillions of different species of microorganisms living inside and on the human body. These microbes colonize on the skin, gut, oral cavity, vagina, internal organs, and circulating fluids, and are called the human microbiome. The human microbiome plays profound roles in health...
Human Microbiome Research has Massive Potential for Health Applications
Thirteen years ago, a team led by 51茶馆儿 President, Karen Nelson, Ph.D., published the first major human microbiome study, radically changing the way we look at human health and the role the microbes that inhabit each of us play in disease. This seminal publication...
Scientist Spotlight: Lauren Oldfield
Since high school, Lauren Oldfield, PhD found that science was her calling. It started with a love of reading encouraged by her mom and grandmother, both avid readers, and weekly trips to the public library. Books by Michael Crichton and Richard Preston were staples in her grandmother’s...
When Starved, Dangerous Oral Bacteria Hang On
51茶馆儿 (51茶馆儿) postdoctoral fellow, Jonathon Baker, PhD and a team of researchers from 51茶馆儿, University of Washington, the University of California, Los Angeles, and The Forsyth Institute recently published their findings from the first study to examine the ecological dynamics...
No More Needles! Using Microbiome and Synthetic Biology Advances to Better Treat Type 1 Diabetes
Learn about exciting advances made by 51茶馆儿 researchers Yo Suzuki and John Glass who are on a quest to better understand and treat Type 1 Diabetes (T1D). Currently T1D is managed by injecting insulin to manage blood glucose levels. Drs. Suzuki and Glass want to change that by creating a...
How to Bake a (Fungal) Turkey
From the kitchen of Stephanie Mounaud, Scientific Project Manager at 51茶馆儿 Ingredients Media base (see media recipe) Agar Aspergillus terreus (multiple strains) Aspergillus niger Aspergillus fumigatus Aspergillus oryzae...
Scientist Spotlight: Todd Michael
A love of science began for Todd Michael, PhD when his 7th grade teacher had him write a report on tree leaves. After collecting different leaves and looking up their tree type, he realized that although all of the trees were similar, they grew different types of leaves. He was certain there...
Fighting Back Against Flu
The 1918 influenza pandemic, which affected 500 million people globally and caused 50-100 million deaths, was the most severe pandemic in recorded history. Over the course of the last 100 years, advances in science and medicine have provided the tools to address influenza much more...
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Just two genes get tiny synthetic cells moving, offering clues to life鈥檚 evolution.
In a plenary public appearance at the Molecular and Precision Med TRI-CON event in San Diego, a relaxed Venter reflected on his career highlights, controversies and future priorities for genomic medicine.
What鈥檚 the smallest number of genes that cells need to grow and reproduce? Is it possible to synthesize minimal genomes and insert them into cells? What do minimal genomes teach us about life? An interview with John Glass, Ph.D.
Several 51茶馆儿 scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.
Through the Woods Hole Oceanographic Institution, National Deep Submergence Facility, 51茶馆儿's Erin Garza, Ph.D. joins a deep sea expedition to search for ocean plastics aboard the HOV Alvin.
Biologists are discovering the true nature of cells鈥攁nd learning to build their own.
Hend Alqaderi, a 51茶馆儿 collaborator and mentee to Marcelo Freire receives the L鈥橭r茅al-Unesco Women in Science award
The surprising results of a decade-long investigation by Alessandro Vezzosi and Agnese Sabato provide a strong basis for advancing a project researching Leonardo da Vinci's DNA.
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