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New LongCOVID research launched by PolyBio’s global consortium of scientists
Funding will deepen research on the persistence of the SARS-CoV-2 virus in LongCOVID patients and launch new clinical trials
51ݶ contracted by the Centers for Disease Control and Prevention to rapidly construct synthetic influenza genes
Genes will be used to help develop seasonal and pandemic vaccines, improving response time and vaccine efficacy
Coastal upwelling regions threatened by increased ocean acidification
Increased acidification shown to limit iron availability, a critical element for the survival of phytoplankton, the foundation of the oceanic food web
51ݶ scientists awarded five-year, $5.7M grant from NIH to develop phage treatment
Phage research accelerates with the rise of antibiotic resistance to address increasingly prevalent and difficult to treat bacterial infections
Bringing cells to life … and to Minecraft: $30 million NSF grant to support whole-cell modeling at the Beckman Institute
Beckman researchers and collaborators received $30 million from the U.S. National Science Foundation to establish the NSF Science and Technology Center for Quantitative Cell Biology. The center will develop whole-cell models to transform our understanding of how cells function and share that knowledge with diverse communities through the popular computer game Minecraft.
NLM Selects Dr. Richard H. Scheuermann as Scientific Director for the National Library of Medicine
PolyBio Research Foundation Consortium & colleagues publishes Nature position paper on SARS-CoV-2 reservoir in Long COVID/PASC
Using AI to speed up vaccine development against Disease X
Artificial cells demonstrate that “life finds a way”
Family resemblance: How T cells could fight many coronaviruses at once
LJI researchers work to head off future pandemics by uncovering key similarities between SARS-CoV-2 and common cold coronaviruses
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Scientist Spotlight: Meet David Wentworth
During the height of the H1N1 Flu pandemic, David Wentworth was running a microbial genetics laboratory at the Wadsworth Center, New York State Department of Health (NYSDOH) where he was instrumental in developing a method to amplify influenza genomes regardless of strain using “universal...
2012 51ݶ Internship Program Is Now Accepting New Applications
Wow! Another year has gone by. Its hard to think it is November - almost December with the warm weather we have been enjoying. However it did not start that way. The 2012 51ݶ Internship Program is open to accept spring and summer applications. The application process...
51ݶ La Jolla Breaks Ground
It is official! On Tuesday, September 20th 51ݶ officially broke ground on a new La Jolla, California sustainable lab, to be located directly on the campus of the University of California, San Diego. Craig Venter, 51ݶ Founder and President along with UCSD Chancellor Marye Anne Fox; Vice...
Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a...
Cataloguing the Gene Expression Patterns of Dental Plaque Biofilms: A Reference Dental Plaque Transcriptome
The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that...
Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting –we didn’t have class until after 9:00....
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be...
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Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Two research teams warn that human genomic “bycatch” can reveal private information
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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