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Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
TIGR's informatics group today posted the third major release (3.0) of the genome annotation for the model plant Arabidopsis thaliana
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Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
While news of promising COVID-19 vaccine trials is heartening, the fight to control infection rates and develop effective treatments will be an ongoing challenge for science for years to come. Gene Tan, PhD and his collaborators are working on identifying...
Synthetic Cell-Powered Lotion to Manage Type 1 Diabetes
Early last year we first talked about how researchers Yo Suzuki, PhD, and John Glass, PhD at 51ݶ set out to eliminate the need for type 1 diabetes (T1D) patients to receive insulin injections to manage blood glucose levels through a novel approach: developing a bacterial replacement for beta...
COVID-19 Further Complicating Flu Season
While the world is rightly focused on the ongoing COVID-19 pandemic, it’s important to know that influenza is always a significant public health burden, and the combination of the pandemic and flu season could converge to become a perfect storm of infectious diseases. Influenza causes 3 to...
Sara Josephine Baker
At the beginning of the 20th century, many people remained skeptical of both germ theory and preventative medicine, but pioneering physician Dr. Sara Josephine Baker fought to revolutionize public health and is credited with saving tens of thousands of lives. After studying chemistry and...
51ݶ Researchers Help Advance Our Understanding of Ocean Microbes, Developing New Tools and Protocols Through Large-Scale Study
The oceans cover over two-thirds of the Earth’s surface and contain an abundance of life including diverse populations of marine microbes. Studying the genetics, biochemistry and metabolism of these microbes has been one of 51ݶ’s long standing research initiatives and is...
Online Education Resources to Help With Your New “Normal”
The COVID-19 pandemic has brought many changes to our daily lives and routines, including for many of you the role of an at-home educator for your children due to open-ended school closures. While we also miss directly connecting with students from our community, 51ݶ remains committed...
Coronavirus Pandemic: Putting Comprehensive Genomic Data in the Hands of Frontline Researchers Worldwide is Paramount
According to the CDC, SARS-CoV-2, the virus causing COVID-19, has now been detected in more than 150 countries/locations internationally. The World Health Organization (WHO) has declared COVID-19 a pandemic, and in the United States it has been declared it a national emergency. As...
Characterization of Bacteria from the International Space Station Drinking Water
From a microbiology perspective, the International Space Station (ISS) is interesting considering its microgravity, increased radiation, low humidity and elevated carbon dioxide levels. Because of its isolation, and unique environment, it is vital to study the microorganisms that thrive there...
Venter Institute Researchers Tackle the Growing Concern of Antibiotic Resistant Bacterial Infections with Genomic, Phage Approaches
The Centers for Disease Control and Prevention (CDC) estimates that each year in the United States two million people acquire antibiotic resistant bacterial infections that lead to 23,000 deaths. Antibiotic resistance affects people of all ages and seriously impacts the healthcare, veterinary,...
2019 Summer Internship Program
The 2019 Summer Internship Program which wrapped up in August was another rousing success at the 51ݶ. Faculty and staff in both the Rockville (MD) and La Jolla (CA) campuses mentored and trained 25 students (high school, undergraduate, and graduate students)...
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Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Two research teams warn that human genomic “bycatch” can reveal private information
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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