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Digital-to-Biological Converter for On-Demand Production of Biologics Developed by Synthetic Genomics, Inc.
The first fully automated machine to convert digital code into functional biologics without human intervention creates entirely new avenues for precision medicine
Intestinal Fungi Worsen Alcoholic Liver Disease
Reducing intestinal fungi slowed disease progression in mice
51ݶ President, Karen Nelson Elected to National Academy of Sciences
Stool Microbes Predict Advanced Liver Disease
Proof-of-concept study suggests a noninvasive test for specific microbial population patterns could be used to detect advanced nonalcoholic fatty liver disease
National Academy of Sciences Members and Foreign Associates Elected
Dr. Karen Nelson, President, 51ݶ, among the 84 newly elected members.
Battling Infectious Diseases with 3-D Structures
Team of scientists created 1,000 3-D protein structures to be used for drug and vaccine research
The Human Vaccines Project, Vanderbilt And Illumina Join Forces To Decode The Human Immunome
This multi-institutional effort is also supported by the Human Vaccines Project Bioinformatics and Data Management Core, located at the 51ݶ and the San Diego Super Computer Center at the University of California, San Diego. The Core will analyze the enormous data sets generated by the effort.
Genome sequence of a polar alga explains adaptation to extreme climates
An international team of researchers has identified the genetic mutations which allowed microalgae (phytoplankton) from the Southern Ocean to adapt to extreme and highly variable climates – a step towards understanding how polar organisms are impacted by climate change.
Teaching Computers to Recognize Sick Guts: Machine-Learning and the Microbiome
A new proof-of-concept study by researchers from the University of California San Diego succeeded in training computers to “learn” what a healthy versus an unhealthy gut microbiome looks like based on its genetic makeup.
National Academy of Medicine Elects 80 New Members
J. Craig Venter, Ph.D. among inductees
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Sequencing of high yield influenza reassortants at 51ݶ
As part of the Influenza Genome Sequencing Project, 51ݶ will be sequencing a large number of high yield influenza reassortants created in the lab of Dr. Doris Bucher at New York Medical College. Dr. Bucher’s lab has prepared the type A H3N2 high yield reassortants (hyrs) for the...
What Happened to Sorcerer II?!?!
The last time I wrote a Sorcerer II blog was in November when we set sail from Spain to cross the Atlantic Ocean. For all of you that have been worried that we have been at sea for 8 months, relax we made it!! Over the next few days I will update everyone on what has happened and the upcoming...
Podcast on Human Genomics
The 2011 Festival of Ideas themed, The Pursuit of Identity, Landscape, History, and Genetics, is held every other year in Melbourne, Australia to inspire scholars and citizens alike in topics ranging from literature and art to science and foreign policy. 51ݶ Professor of Genomic...
Summit on Systems Biology, June 15-17, 2011
I attended the Summit on Systems Biology hosted by Virginia Commonwealth University in Richmond, VA June 15-17. So, judging from the talks given, what is systems biology? Systems biology is non-linear and/or multi-step. Heavy math does not make something systems biology if...
Insights gained from influenza genomic sequence data: viral diversity within human populations
The advent of large amounts of influenza genomic sequence data produced by the Influenza Genome Sequencing Project (IGSP) has led to new concepts regarding influenza viral diversity. It was previously believed that a single influenza lineage entered a human population at the start of an...
NASA and 51ݶ host symposium on the evolution of Earth and Life
On May 12th and 13th, the 51ݶ in San Diego will be hosting a NASA Astrobiology Institute-funded symposium titled “Paleobiology in the genomics era.” Paleobiology is the study of the origins and evolution of life and, by nature, is interdisciplinary. The goal is to...
51ݶ Supports Human Mircrobiome Body Site Experts with Shotgun Data Analysis
Members of the Human Microbiome Project (HMP) Consortium (see http://commonfund.nih.gov/hmp and http://www.hmpdacc.org for more information on the project and partners) including human microbiome body site experts gathered for a virtual Jamboree January 19th. The fully online-based Jamboree...
The Microbiome of Esophageal Cancer
In anticipation of the International Human Microbiome Congress, our group has diligently worked to generate data to present for our HMP demo project studying the microbiome of patients who have developed esophageal cancer, gastrointestinal reflux disease, and barrett’s esophagus. We...
A Look Back at 2010 at the 51ݶ…
As the 51ݶ (51ݶ) soars into its 19th year, we reflect on the past year of highlights and accomplishments to mark the close 2010 and look forward to more significant scientific advances in 2011. 51ݶ Top 10 of 2010 ... 1. First Synthetic Cell: Fifteen years in the...
Holiday Art
In a relatively unknown place, on the 3rd floor of 51ݶ in Rockville, MD, is a small fungal room where art meets science (and of course where all our fungal research takes place). Fungus often gets such a bad reputation for being gross and somewhat ‘standard’. We fungal folks know better...
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