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16TH International Genome Sequencing and Analysis Conference Features NIAID Director Anthony Fauci, Biologist E.O. Wilson and other Eminent Scientists
Conference in Washington, DC, highlights cutting-edge work in environmental genomics, human genomic medicine, biological energy production, evolutionary biology, and new sequencing technologies
GSAC also hosts half-day policy session on biodiversity and intellectual property issues
Scientists Explore Genome of Methane-breathing Microbe
First Complete DNA Sequence of a Methanotroph Reveals Metabolic Flexibility, Suggests Mechanisms for Increasing Its Usefulness For Biotechnology
TIGR Scientists Explore Microbes on Shipwrecks and Coral
Researchers embarked on two separate expeditions this week to explore microbial communities on deep-sea corals in the Gulf of Alaska and on shipwrecks in the Gulf of Mexico.
Bioinformatics Resource Center at TIGR to Focus on Biothreat Pathogens
TIGR has signed a five-year, $21.1 million contract with the National Institute of Allergy and Infectious Diseases to establish and maintain a new national Bioinformatics Resource Center for the study of pathogens that are considered biothreat agents or are associated with emerging or re-emerging infectious diseases.
Anthrax Toxin Genes Found in Another Microbial Species
For the first time, researchers have found anthrax toxin genes in a naturally occurring microbe other than Bacillus anthracis, the bacterium that causes anthrax. The microbe that contains those anthrax genes is a strain of Bacillus cereus isolated from a patient with a medical condition similar to inhalation anthrax.
Decoding a Sulfate-Breathing Bug
Paving the way for better methods to protect pipelines and remediate metallic pollutants, TIGR scientists and collaborators have deciphered the genome of a sulfate-breathing bacterium, Desulfovibrio vulgaris, which can damage oil and natural gas pipelines and corrode oilfield equipment.
Scientists Decipher the Rat Genome
An international consortium of scientists that includes TIGR has completed a high-quality draft sequence of the rat genome. Comparing the rat to the human and mouse genomes, the Rat Genome Sequencing Project Consortium reported that nearly all human genes known to be associated with diseases have counterparts in the rat.
HP and TCAG Collaborate to Advance Medical and Environmental Genomic Discovery in Life Science
A New Spin on Spirochetes
Major Differences Found Between the Genomes of Oral Pathogen Treponema denticola and Related Spiral-Shaped Bacteria that Cause Syphilis and Lyme Disease
"Male-Targeting" Bacterium's Genome is Deciphered
Versatile Wolbachia has more mobile DNA than any other intracellular bacterium; Study may help in developing new treatments for diseases
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Scientist Spotlight: Meet David Wentworth
During the height of the H1N1 Flu pandemic, David Wentworth was running a microbial genetics laboratory at the Wadsworth Center, New York State Department of Health (NYSDOH) where he was instrumental in developing a method to amplify influenza genomes regardless of strain using “universal...
2012 51茶馆儿 Internship Program Is Now Accepting New Applications
Wow! Another year has gone by. Its hard to think it is November - almost December with the warm weather we have been enjoying. However it did not start that way. The 2012 51茶馆儿 Internship Program is open to accept spring and summer applications. The application process...
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Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a...
Cataloguing the Gene Expression Patterns of Dental Plaque Biofilms: A Reference Dental Plaque Transcriptome
The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that...
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We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting –we didn’t have class until after 9:00....
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be...
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