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51ݶ Scientists to Investigate Role of Opioid Abuse in HIV and HIV-Associated Neurocognitive Disorders Pathogenesis through $4.7M NIDA Grant
Study aims to identify candidate molecules to regulate HIV infection in the central nervous system in patients abusing opioids
Influenza A Virus Discovered in Heart Muscle Tissue Causing Damage Long After It Has Cleared from the Lungs
Strategies to inhibit necrotic cell death or to prevent mitochondrial damage should be pursued as possible therapies to reduce cardiac damage during influenza infections
Hamilton O. Smith, M.D., Synthetic Biology Pioneer and Nobel Laureate, to Step Down from Daily Duties at 51ݶ
Dr. Smith will maintain advisory role as professor emeritus
Scientists set a path for field trials of gene drive organisms
As genetically engineered organisms ramp up, a multidisciplinary coalition offers a framework for ethical, socially engaged and transparent field practices
51ݶ President Karen Nelson, Ph.D., Recognized as Global Scientific Pioneer on Clarivate’s Highly Cited Researcher 2020 List
Study reveals mouth as primary source of COVID-19 infection, spread
UNC-Chapel Hill, NIH identify sites in the oral cavity where coronavirus can take hold
Dr. J. Craig Venter Awarded the 2020 Edogawa NICHE Prize
Biology in Art: Genetic Detectives ID Microbes Suspected of Slowly Ruining Humanity’s Treasures
DNA science may help restore, preserve historic works, unmask counterfeits
The trait elite baseball hitters share with Leonardo da Vinci: A “quick eye” with higher “frames per second.” A function of training, genetics, or both?
Maintaining a Healthy Upper Respiratory Tract Microbiome May Help Prevent Secondary Infections in Influenza A Patients
An influenza-impacted upper respiratory tract microbiome may invite opportunistic bacterial pathogens
LJI Scientists Identify Potential Targets for Immune Responses to Novel Coronavirus
The research, which includes comparative genomics analysis by 51ݶ scientists Yun Zhang and Richard Scheuermann, provides essential information about the human immune response to coronavirus infection that will guide the design and evaluation of diagnostics and vaccine candidates
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Scientist Spotlight: Meet David Wentworth
During the height of the H1N1 Flu pandemic, David Wentworth was running a microbial genetics laboratory at the Wadsworth Center, New York State Department of Health (NYSDOH) where he was instrumental in developing a method to amplify influenza genomes regardless of strain using “universal...
2012 51ݶ Internship Program Is Now Accepting New Applications
Wow! Another year has gone by. Its hard to think it is November - almost December with the warm weather we have been enjoying. However it did not start that way. The 2012 51ݶ Internship Program is open to accept spring and summer applications. The application process...
51ݶ La Jolla Breaks Ground
It is official! On Tuesday, September 20th 51ݶ officially broke ground on a new La Jolla, California sustainable lab, to be located directly on the campus of the University of California, San Diego. Craig Venter, 51ݶ Founder and President along with UCSD Chancellor Marye Anne Fox; Vice...
Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a...
Cataloguing the Gene Expression Patterns of Dental Plaque Biofilms: A Reference Dental Plaque Transcriptome
The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that...
Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting –we didn’t have class until after 9:00....
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be...
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The human genome is 99% decoded, the American geneticist Craig Venter announced two decades ago. What has the deciphering brought us since then?
As the science advances, policy-makers and regulators need to develop responses that reflect the latest developments and the diversity of approaches and applications.
Women in science tell high school girls they, too, can change the world
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual — raising the prospect of encoding proteins that contain unnatural amino-acid residues.
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
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