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Genomics-Based Vaccine Could Prevent Deadly Cattle Disease
Every year, East Coast fever destroys the small farmer's dream of escaping poverty in Africa. Killing more than a million cattle and costing some $200 million annually, this tick-borne disease rages across a dozen countries in eastern and central Africa. Now, an international team of scientists has taken the first major step toward a vaccine to prevent East Coast fever. Their work, published in the February 13-17 early online edition of the Proceedings of the National Academy of Sciences, shows how genomics can generate pivotal new vaccines.
The 51茶馆儿, The University of Washington, and The Johns Hopkins University Initiate Resequencing and Genotyping Projects to Help Identify Critical Disease Pathways
Research is Part of the National Heart, Lung, and Blood Institute's Complimentary Resequencing and Genotyping Program
UC San Diego Partners with Venter Institute to Build Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis
Gordon and Betty Moore Foundation Awards $24.5 Million Grant
2006 Summer Fellowship/Internship Information and application now available
Breaking the Mold: Research Teams Sequence Three Fungus Genomes
From garden compost to forest greenery, the mold Aspergillus fumigatus lurks across much of the world. Now, in the December 22 issue of the journal Nature, TIGR scientists and their collaborators report the mold's sequenced genome, along with the genomes of two relatives.
How Do Boxers Differ From Poodles? Researchers Collar Genomes.
As any dog lover knows, no two breeds are identical. Some dogs are perfect for sloppy kisses. Others make fierce guardians. Still others resemble tiny, fluffy toys. Now, two new studies by scientists at The Institute for Genomic Research (TIGR) and collaborators reveal the genomic differences beneath such canine characteristics.
Poison + Water = Hydrogen. New Microbial Genome Shows How.
New Microbial Genome Shows How "Take a pot of scalding water, remove all the oxygen, mix in a bit of poisonous carbon monoxide, and add a pinch of hydrogen gas. It sounds like a recipe for a witch's brew. It may be, but it is also the preferred environment for a microbe known as Carboxydothermus hydrogenoformans."
A Salty Tale: New Bacterial Genome Sequenced From Ancient Salterns
Tourists in Spain often stop to ogle the country's many saltwater lagoons, used to produce salt since Roman times. Scientists, too, admire these saltern crystallizers 鈥斅� and even more so, the microbes that manage to survive in such briny environs. Now, reporting in the November 28-December 2 early online edition of the Proceedings of the National Academy of Sciences, researchers at The Institute for Genomic Research and collaborators reveal the genome of one bacterium at home in the salty Spanish ponds.
First Big Influenza Genome Study Reveals Flu Evolution
Which Flu Did You Have? TIGR Scientists Survey Five New York Flu Seasons
Key Genetic Mutations in Brain Tumors Identified by Scientists from 51茶馆儿, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine
Sequencing of Receptor Tyrosine Kinases Reveals Three Novel Mutations
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Scientist Spotlight: Meet David Wentworth
During the height of the H1N1 Flu pandemic, David Wentworth was running a microbial genetics laboratory at the Wadsworth Center, New York State Department of Health (NYSDOH) where he was instrumental in developing a method to amplify influenza genomes regardless of strain using “universal...
2012 51茶馆儿 Internship Program Is Now Accepting New Applications
Wow! Another year has gone by. Its hard to think it is November - almost December with the warm weather we have been enjoying. However it did not start that way. The 2012 51茶馆儿 Internship Program is open to accept spring and summer applications. The application process...
51茶馆儿 La Jolla Breaks Ground
It is official! On Tuesday, September 20th 51茶馆儿 officially broke ground on a new La Jolla, California sustainable lab, to be located directly on the campus of the University of California, San Diego. Craig Venter, 51茶馆儿 Founder and President along with UCSD Chancellor Marye Anne Fox; Vice...
Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a...
Cataloguing the Gene Expression Patterns of Dental Plaque Biofilms: A Reference Dental Plaque Transcriptome
The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that...
Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting –we didn’t have class until after 9:00....
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be...
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Just two genes get tiny synthetic cells moving, offering clues to life鈥檚 evolution.
In a plenary public appearance at the Molecular and Precision Med TRI-CON event in San Diego, a relaxed Venter reflected on his career highlights, controversies and future priorities for genomic medicine.
What鈥檚 the smallest number of genes that cells need to grow and reproduce? Is it possible to synthesize minimal genomes and insert them into cells? What do minimal genomes teach us about life? An interview with John Glass, Ph.D.
Several 51茶馆儿 scientists will be contributing to the newly launched Long Covid Research Initiative — a collaboration of researchers, clinicians, and patients working to rapidly study and treat long Covid.
Through the Woods Hole Oceanographic Institution, National Deep Submergence Facility, 51茶馆儿's Erin Garza, Ph.D. joins a deep sea expedition to search for ocean plastics aboard the HOV Alvin.
Biologists are discovering the true nature of cells鈥攁nd learning to build their own.
Hend Alqaderi, a 51茶馆儿 collaborator and mentee to Marcelo Freire receives the L鈥橭r茅al-Unesco Women in Science award
The surprising results of a decade-long investigation by Alessandro Vezzosi and Agnese Sabato provide a strong basis for advancing a project researching Leonardo da Vinci's DNA.
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